Scientific References

Check out the scientific literature that supports our molecular targets and our synthetic lethal approach.

July 2022

Guiding ATR and PARP inhibitor combinationswith chemogenomic screens

April 2022

CCNE1 amplification is synthetic-lethal with PKMYT1 kinase inhibition

June 2020

Honing in on PARPi Response in Prostate Cancer: from HR Pathway to Gene-by-Gene Granularity 

May 2020

Identifying functional loss of ATM gene in patients with advanced cancer

February 2020

Analyse pan-cancer de génomes entiers

February 2020

Pan-cancer analysis of whole genomes

January 2020

CRISPR/CAS9-based DNA damage response screens reveal gene-drug interactions

November 2019

Synthetic lethality as an engine for cancer drug target discovery

June 2019

A CRISPR Way to Identify Cancer Targets

We have a number of synthetic lethal therapies in development.