Scientific References

Check out the scientific literature that supports our molecular targets and our synthetic lethal approach.

January 2020

CRISPR/CAS9-based DNA damage response screens reveal gene-drug interactions

November 2019

Synthetic lethality as an engine for cancer drug target discovery

June 2019

A CRISPR Way to Identify Cancer Targets

April 2018

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

September 2016

Synthetic lethality in lung cancer and translation to clinical therapies

November 2015

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

February 2004

Global mapping of the yeast genetic interaction network

We have a number of synthetic lethal therapies in development.